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KMID : 1164220080200010011
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Journal of Korean Society for Radiotherapeutic Technology
2008 Volume.20 No. 1 p.11 ~ p.15
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Dosimetric Comparison of Three Dimensional Conformal Radiation Radiotherapy and Helical Tomotherapy Partial Breast Cancer
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Kim Dae-Woong
Kim Jong-Won
Choi Yun-Kyeung
Kim Jung-Soo
Hwang Jae-Woong
Jeong Kyeong-Sik
Choi Gye-Sook
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Abstract
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Purpose: The goal of radiation treatment is to deliver a prescribed radiation dose to the target volume accurately
while minimizing dose to normal tissues. In this paper, we comparing the dose distribution between three dimensional conformal radiation radiotherapy (3D-CRT) and helical tomotherapy (TOMO) plan for partial breast cancer.
Materials and Methods: Twenty patients were included in the study, and plans for two techniques were developed for each patient (left breast:10 patients, right breast:10 patients). For each patient 3D-CRT planning was using
pinnacle planning system, inverse plan was made using Tomotherapy Hi-Art system and using the same targets and
optimization goals. We comparing the Homogeneity index (HI), Conformity index (CI) and sparing of the organs at risk for dose-volume histogram.
Results: Whereas the HI, CI of TOMO was significantly better than the other, 3D-CRT was observed to have
significantly poorer HI, CI. The percentage ipsilateral non-PTV breast volume that was delivered 50% of the prescribed dose was 3D-CRT (mean: 40.4%), TOMO (mean: 18.3%). The average ipsilateral lung volume percentage receiving 20% of the PD was 3D-CRT (mean: 4.8%), TOMO (mean: 14.2), concerning the average heart volume receiving 20% and 10% of the PD during treatment of left breast cancer 3D-CRT (mean: 1.6%, 3.0%), TOMO (mean: 9.7%, 26.3%)
Conclusion: In summary, 3D-CRT and TOMO techniques were found to have acceptable PTV coverage in our
study. However, in TOMO, high conformity to the PTV and effective breast tissue sparing was achieved at the expense of considerable dose exposure to the lung and heart.
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KEYWORD
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breast cancer, 3D-CRT, helical tomotherapy, TOMO
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